Reproducibility and replicability of rodent phenotyping in preclinical studies

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Reproducibility and replicability of rodent phenotyping in preclinical studies

The scientific community is increasingly concerned with the proportion of published "discoveries" that are not replicated in subsequent studies. The field of rodent behavioral phenotyping was one of the first to raise this concern, and to relate it to other methodological issues: the complex interaction between genotype and environment; the definitions of behavioral constructs; and the use of l...

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Replicability and Reproducibility in Comparative Psychology

Psychology faces a replication crisis. The Reproducibility Project: Psychology sought to replicate the effects of 100 psychology studies. Though 97% of the original studies produced statistically significant results, only 36% of the replication studies did so (Open Science Collaboration, 2015). This inability to replicate previously published results, however, is not limited to psychology (Ioan...

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ژورنال

عنوان ژورنال: Neuroscience & Biobehavioral Reviews

سال: 2018

ISSN: 0149-7634

DOI: 10.1016/j.neubiorev.2018.01.003